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Urinary incontinence may be caused by an underdeveloped urinary system or may arise as a part of the aging process. Estrogen deficiency is the most common cause of incontinence in spayed female dogs and may result in weakened muscles in the bladder and sphincter causing urine leakage. Bovine ovary powder nutritionally provides natural estrogens and works synergistically with the phytoestrogens provided by licorice, wild yam and other ingredients. Research indicates that phyto-estrogens may help strengthen the bladder and sphincter muscles and improve muscle tone. Suggested Use: Up to 50lbs...1 tablet twice daily, 50 to 75lbs...2 tablets twice daily, Over 75lbs...3 tablets twice daily Tablets may be give orally or crumbled and mixed with moist food. Responses to natural dietary supplements may vary by animal. One tablet guaranteed to contain: Wild Yam Root...315mg, Bee Pollen...210mg, Rehmannia...158mg, Angelica Sinesis...79mg, Psoralea...79mg, Glandalia...53mg, Licorice...21mg Ingredients: A proprietary of Bone Meal, Wild Yam Root, Bee Pollen, Rehmannia, Microcrystalline Cellulose, Psoralea, Angelica Sinesis, Glandalai, Glyceryl Monostearate, Licorice, Croscarmellose Sodium, Magnesium Stearate, and Silica Dioxide