Ark Naturals NEEM "PROTECT" Sprayuses environmentally friendly and natural botanicals. Gentle and non-drying, smoothes itching and irritation.Neem and citronella have been used for thousands of years by the people of India, Southeast Asia and Africa. Scientists have found that these plants contain compounds that are unpalatable to biting insects.Ark Naturals neem oil comes directly from the seed of the neem tree. Neem oils and extracts have antimicrobial, anti-inflammatory and would healing properties. Neem "Protect" Sprayis specifically designed to soothe irritated skin inflamed from insect bites, hot spots and other skin and coat issues. Regular use may help reduce the risk of infections, itching and dermatitis caused by insect bites or other skin and coat conditions.Safe and effective for use on adult dogs and cats, puppies and kittens 6 weeks and older, and all large animals. Safe for human use.